THERMO FISHER ORBITRAP

University of Salzburg

Salzburg | Website

Open for Collaboration

Short Description

Quadrupole ion trap–Orbitrap mass spectrometer with collision-, electron transfer-, or laser-induced fragmentation for use in proteomics and metabolomics analysis.

Sample introduction via direct infusion using a syringe pump or via (nano) HPLC; equipped with ESI and nano-ESI sources. A dedicated protein mode up to m/z 16,000 makes the system particularly suitable for intact protein measurements. Additionally, a high-resolution option of up to 480,000 is available.

Software packages for the analysis of bottom-up and top-down proteomics data, metabolite identification, and fragment analysis.

Contact Person

Prof. Dr. Christian Huber

Research Services

Proteomic and metabolomic measurements, proteinsequences and post-translational modifications

Methods & Expertise for Research Infrastructure

The device is used for the highly sensitive detection and identification of biomolecules based on their accurate mass or on fragmentation spectra. With the help of such measurements, for example, protein expression profiles, the chemical structure of protein therapeutics, the cargo of extracellular vesicles, or drug degradation products can be analyzed.

Allocation to research infrastructure

Bioanalytics