IVDr AVANCE NEO 600 MHz-Spektrometer inkl. Hard/Software

Die Nutzungsbedingungen wurden in einer Nutzervereinbarung festgelegt und können hier abgerufen werden:
https://box.medunigraz.at/s/b3QojWtTzDdP5ds

Universität Graz
Technische Universität Graz
BioTechMed-Graz
Medizinische Universität Innsbruck
Medizinische Universität Wien
Universität Wien
Technische Universität Wien
Diverse europäische Universitäten im Rahmen von gemeinsamen Projekten
Internationale Kooperationen

Austrian Science Fund (FWF)
- Cluster of Excellence Metabolic control of aging and disease (METAGE), 2024-2029, Tobias Madl & MetAGE Consortium, https://www.fwf.ac.at/en/discover/excellentaustria/clusters-of-excellence, https://www.metage.at
- doc.fund Biomolecular Structures and Interactions (BioMolStruct), 2021-2025, Tobias Madl & BioMolStruct Consortium, https://www.medunigraz.at/en/doctoral-programs/phd-programm/biomolecular-structures-and-interactions-biomolstruct, https://www.fwf.ac.at/en/research-radar/10.55776/DOC130
- DK Metabolic and Cardiovascular Disease (DK-MCD), 2019-2023, Tobias Madl & DK-MCD Consortium, https://www.medunigraz.at/DK_MCD/
- Regulation of RGG-mediated Nuclear Import, 2018-2022, Tobias Madl, https://www.fwf.ac.at/en/research-radar/10.55776/I3792

Austrian Research Promotion Agency (FFG)
- Next Generation NMR-based Metabolomics (NextGen metNMR), 2024-2027, Tobias Madl, https://projekte.ffg.at/projekt/5123266
- Next-generation X-ray platform for integrative structural biology, 2019-2023, Tobias Madl, https://projekte.ffg.at/projekt/3148514

Styrian Government
- doc.fund Biomolecular Structures and Interactions (BioMolStruct), 2021-2025, Tobias Madl, https://www.medunigraz.at/en/doctoral-programs/phd-programm/biomolecular-structures-and-interactions-biomolstruct
- Future Funds Frontier NMR, 2019-2020, Tobias Madl & Klaus Zangger, https://www.zukunftsfonds.steiermark.at/cms/ziel/146410193/DE/

BioTechMed
- Flagship project Dynamics of subcellular partitioning through protein modification, 2020-2023, Tobias Madl & Flagship Consortium, https://biotechmedgraz.at/en/programs/flagship-projects/dynimo/

ÖAD Scientific & Technological Cooperation
- 2026-2027, Tobias Madl, https://oead.at/de/kooperationen/internationale-hochschulkooperationen/wissenschaftlich-technische-zusammenarbeit

Vollständige Publikationsliste:
https://pubmed.ncbi.nlm.nih.gov/?term=madl+t&filter=years.2017-2026&sort=date

Auswahl (2021-2026):

2026
1. Konrad B, Bluemel G, Haitzmann T, Frech T, Vandekeere A, Planque M, Bubalo V, Schindlmaier K, Jäger V, Dengler MA, Stryeck S, Brcic L, Lindenmann J, Stiegler P, Bresilla D, Madreiter-Sokolowski CT, Madl T, Eichmann TO, Kneidinger N, Fendt SM, Leithner K. A shift in the cellular redox state redirects aspartate for export under glucose deprivation. Cancer Metab. 2026 Mar 3;14(1):4. doi: 10.1186/s40170-026-00420-x. PMID: 41776691.
2. Mohammadzadeh R, Mahnert A, Zurabishvili T, Wink L, Kumpitsch C, Habisch H, Sprengel J, Filek K, Mertelj P, Pernitsch D, Hingerl K, Durdevic M, Gorkiewicz G, Diener C, Loy A, Kolb D, Trautwein C, Madl T, Moissl-Eichinger C. Cross-domain metabolic interactions link Methanobrevibacter smithii to colorectal cancer microbial ecosystems. Nat Commun. 2026 Feb 20. doi: 10.1038/s41467-026-69711-7. Epub ahead of print. PMID: 41720792.
3. Horvath A, Haller R, Schmid-Zalaudek K, Goswami N, Wagner-Skacel J, Habisch H, Madl T, Stadlbauer V. The beneficial effect of a multispecies probiotic intervention on quality of sleep - a randomized, double-blinded, placebo-controlled study. J Psychiatr Res. 2026 Apr;195:244-256. doi: 10.1016/j.jpsychires.2026.01.040. Epub 2026 Jan 28. PMID: 41637999.
4. Haller R, Hazia O, Feldbacher N, Traub J, Madl T, Habisch H, Horvath A, Stadlbauer V. Nitrogen recycling by the gut microbiome in sarcopenia. Front Microbiol. 2026 Jan 5;16:1698437. doi: 10.3389/fmicb.2025.1698437. PMID: 41561025; PMCID: PMC12812614.
5. Klobučar I, Pregartner G, Rechberger G, Eichmann TO, Potočnjak I, Trbušić M, Habisch H, Pfeifer B, Madl T, Berghold A, Frank S, Degoricija V. Low Serum Lysophospholipids Predict Increased In-Hospital Mortality in Patients With Acute Heart Failure. J Am Heart Assoc. 2026 Jan 20;15(2):e043828. doi: 10.1161/JAHA.125.043828. Epub 2026 Jan 19. PMID: 41553073; PMCID: PMC12919526.

2025
6. Habich D, Horvath A, Feldbacher N, Rebol L, Nepel M, Madl T, Habisch HJ, Baumann-Durchschein F, Fürst S, Plank J, Rainer F, Spindelböck W, Stauber RE, Tatscher E, Wagner M, Zollner G, Stadlbauer V. An observational study on the effect of l-ornithine-l-aspartate (LOLA) on the gut microbiome in liver cirrhosis. A single center phase 4 study. Clin Nutr. 2026 Jan;56:106522. doi: 10.1016/j.clnu.2025.11.007. Epub 2025 Nov 29. PMID: 41406626.
7. Conde R, Gil-Redondo R, Bizkarguenaga M, Lodge S, Nitschke P, de Diego Á, González-Valle B, Hui J, Hunter ML, Yeap BB, Cenarro A, Lope V, Habisch H, Haudum C, Verheyen N, Obermayer-Pietsch B, Zaro Bastanzuri MJ, González Fernández MR, Fernández-Bergés D, Salazar AM, Sorando-Fernandez MP, Meijide S, Hernandez G, Arana E, Seco ML, Sousa A, Oliveira N, Verde I, Madl T, Unda-Urzaiz M, Carracedo A, Diercks T, Castelló A, Schäfer H, Spraul M, Cannet C, Embade N, Valenti L, Civeira F, Lu SC, Holmes E, Wist J, Nicholson JK, Mato JM, Millet O. Age- and sex-specific lipoprotein profiles in general and cardiometabolic population cohorts. EBioMedicine. 2025 Dec;122:106021. doi: 10.1016/j.ebiom.2025.106021. Epub 2025 Nov 8. PMID: 41207221; PMCID: PMC12648477.
8. Panzitt K, Jungwirth E, Vosko LE, Madreiter-Sokolowski CT, Madl T, Tawfik I, Habisch H, Krstic J, Prokesch A, Karitnig R, Sucher R, Erdogan CY, Vallim TA, Trauner M, Fickert P, Al-Dury S, Molinaro A, Moore DD, Thallinger GG, Marschall HU, Wagner M. FXR adapts hepatic mitochondrial function to increased substrate oxidation in patients with obesity. Sci Transl Med. 2025 Aug 13;17(811):eadn4558. doi: 10.1126/scitranslmed.adn4558. Epub 2025 Aug 13. PMID: 40802742.
9. Bourgeois B, Spreitzer E, Platero-Rochart D, Paar M, Zhou Q, Usluer S, de Keizer PLJ, Burgering BMT, Sánchez-Murcia PA, Madl T. The disordered p53 transactivation domain is the target of FOXO4 and the senolytic compound FOXO4-DRI. Nat Commun. 2025 Jul 1;16(1):5672. doi: 10.1038/s41467-025-60844-9. PMID: 40593617.
10. Pammer A, Madl T, Habisch H, Kerbl-Knapp J, Rainer F, Stadlbauer V, Horvath A, Douschan P, Stauber RE, Marsche G. Depletion of Small HDL Subclasses Predicts Poor Survival in Liver Cirrhosis. Antioxidants (Basel). 2025 May 30;14(6):664. doi: 10.3390/antiox14060664. PMID: 40563298.
11. Zhou Q, Sagmeister T, Hutten S, Bourgeois B, Pavkov-Keller T, Dormann D, Madl T. Structural basis of phosphorylation-independent nuclear import of CIRBP by TNPO3. Nat Commun. 2025 May 14;16(1):4456. doi: 10.1038/s41467-025-59802-2. PMID: 40360518.
12. Reiter BF, Bordag N, Schnoegl D, Delbeck M, Madl T, Habisch H, Kwapiszewska G, Meding J, Marsh LM. The Acrolein - Lipopolysaccharide Mouse Model for Frequent Exacerbations in COPD. Am J Respir Cell Mol Biol. 2025 May 9. doi: 10.1165/rcmb.2024-0507MA. Epub ahead of print. PMID: 40343865.
13. Weinberger V, Mohammadzadeh R, Blohs M, Kalt K, Mahnert A, Moser S, Cecovini M, Mertelj P, Zurabishvili T, Arora B, Wolf J, Shinde T, Madl T, Habisch H, Kolb D, Pernitsch D, Hingerl K, Metcalf W, Moissl-Eichinger C. Expanding the cultivable human archaeome: Methanobrevibacter intestini sp. nov. and strain Methanobrevibacter smithii 'GRAZ-2' from human faeces. Int J Syst Evol Microbiol. 2025 Apr;75(4). doi: 10.1099/ijsem.0.006751. PMID: 40237437.
14. Olivos-Ramirez GE, Cofas-Vargas LF, Madl T, Poma AB. Conformational and Stability Analysis of SARS-CoV-2 Spike Protein Variants by Molecular Simulation. Pathogens. 2025 Mar 12;14(3):274. doi: 10.3390/pathogens14030274. PMID: 40137759.
15. Semmler G, Baumgartner C, Metz M, Gensluckner S, Habisch H, Hofer H, März W, Offner F, Völkerer A, Petrenko O, Wernly B, Draxler-Dworzak S, Neyer M, Nigmann C, Greber-Platzer S, Esterbauer H, Madl T, Aigner E, Scherer T, Datz C. Lipid Dysregulation in Tangier Disease: A Case Series and Metabolic Characterization. J Clin Endocrinol Metab. 2025 Mar 3:dgaf131. doi: 10.1210/clinem/dgaf131. Epub ahead of print. PMID: 40037526.
16. Okutan B, Schwarze UY, Habisch H, Iskhakova K, Ćwieka H, Ribeiro-Machado C, Moosmann JP, Blanchet C, Brcic I, Santos SG, Madl T, Zeller-Plumhoff B, Weinberg AM, Wieland DCF, Sommer NG. Biodegradable ultrahigh-purity magnesium and its alloy ZX00 promote osteogenesis in the medullary cavity and glycogenolysis in the liver. Acta Biomater. 2025 Feb 5:S1742-7061(25)00094-7. doi: 10.1016/j.actbio.2025.02.007. Epub ahead of print. PMID: 39921183.
17. Akhmetshina A, Schooltink L, Amor M, Kuentzel KB, Rainer S, Nandy A, Habisch H, Madl T, Rendina-Ruedy E, Leithner K, Vujić N, Kratky D. Loss or inhibition of lysosomal acid lipase in vitro leads to cholesteryl ester accumulation without affecting muscle formation or mitochondrial function. BBA Adv. 2024 Dec 25;7:100135. doi: 10.1016/j.bbadva.2024.100135. PMID: 39839442; PMCID: PMC11745973.

2024
18. Stadler JT, Borenich A, Pammer A, Emrich IE, Habisch H, Madl T, Heine GH, Marsche G. Association of Small HDL Subclasses with Mortality Risk in Chronic Kidney Disease. Antioxidants (Basel). 2024 Dec 11;13(12):1511. doi: 10.3390/antiox13121511. PMID: 39765838.
19. Horvath A, Haller R, Feldbacher N, Habisch H, Žukauskaitė K, Madl T, Stadlbauer V. Probiotic Therapy of Gastrointestinal Symptoms During COVID-19 Infection: A Randomized, Double-Blind, Placebo-Controlled, Remote Study. Nutrients. 2024 Nov 20;16(22):3970. doi: 10.3390/nu16223970. PMID: 39599756.
20. Horvath A, Habisch H, Prietl B, Pfeifer V, Balazs I, Kovacs G, Foris V, John N, Kleinschek D, Feldbacher N, Grønbæk H, Møller HJ, Žukauskaitė K, Madl T, Stadlbauer V. Alteration of the Gut-Lung Axis After Severe COVID-19 Infection and Modulation Through Probiotics: A Randomized, Controlled Pilot Study. Nutrients. 2024 Nov 8;16(22):3840. doi: 10.3390/nu16223840. PMID: 39599626.
21. Michenthaler H, Duszka K, Reinisch I, Galhuber M, Moyschewitz E, Stryeck S, Madl T, Prokesch A, Krstic J. Systemic and transcriptional response to intermittent fasting and fasting-mimicking diet in mice. BMC Biol. 2024 Nov 20;22(1):268. doi: 10.1186/s12915-024-02061-2. PMID: 39567986.
22. Hornegger H, Anisimova AS, Muratovic A, Bourgeois B, Spinetti E, Niedermoser I, Covino R, Madl T, Karagöz GE. IGF2BP1 phosphorylation in the disordered linkers regulates ribonucleoprotein condensate formation and RNA metabolism. Nat Commun. 2024 Oct 20;15(1):9054. doi: 10.1038/s41467-024-53400-4. PMID: 39426983.
23. Šimunić E, Podgorski II, Pinterić M, Hadžija MP, Belužić R, Paradžik M, Dončević L, Balog T, Kaloper M, Habisch H, Madl T, Korać A, Sobočanec S. Sirtuin 3 drives sex-specific responses to age-related changes in mouse embryonic fibroblasts. Mech Ageing Dev. 2024 Oct 10:111996. doi: 10.1016/j.mad.2024.111996. Epub ahead of print. PMID: 39395563.
24. Klobučar I, Habisch H, Klobučar L, Trbušić M, Pregartner G, Berghold A, Kostner GM, Scharnagl H, Madl T, Frank S, Degoricija V. Sex-Related Differences in the Associations between Adiponectin and Serum Lipoproteins in Healthy Subjects and Patients with Metabolic Syndrome. Biomedicines. 2024 Sep 1;12(9):1972. doi: 10.3390/biomedicines12091972. PMID: 39335486; PMCID: PMC11429094.
25. Pammer A, Obermayer A, Stadler JT, Pferschy PN, Tripolt NJ, Habisch H, Madl T, Sourij H, Marsche G. Effects of dietary interventions and intermittent fasting on HDL function in obese individuals with T2DM: a randomized controlled trial. Cardiovasc Diabetol. 2024 Sep 12;23(1):339. doi: 10.1186/s12933-024-02426-5. PMID: 39267053.
26. Bradić I, Vujić N, Kuentzel KB, Habisch H, Pirchheim A, Akhmetshina A, Henderson JD, Madl T, Deshmukh AS, Kratky D. Lanifibranor Reduces Inflammation and Improves Dyslipidemia in Lysosomal Acid Lipase-Deficient Mice. Gastro Hep Adv. 2024 May 28;3(6):711-723. doi: 10.1016/j.gastha.2024.05.006. PMID: 39280921; PMCID: PMC11401563.
27. Pammer A, Klobučar I, Stadler JT, Meissl S, Habisch H, Madl T, Frank S, Degoricija V, Marsche G. Impaired HDL antioxidant and anti-inflammatory functions are linked to increased mortality in acute heart failure patients. Redox Biol. 2024 Sep 5;76:103341. doi: 10.1016/j.redox.2024.103341. Epub ahead of print. PMID: 39244794.
28. Madreiter-Sokolowski CT, Hiden U, Krstic J, Panzitt K, Wagner M, Enzinger C, Khalil M, Abdellatif M, Malle E, Madl T, Osto E, Schosserer M, Binder CJ, Olschewski A. Targeting organ-specific mitochondrial dysfunction to improve biological aging. Pharmacol Ther. 2024 Aug 21:108710. doi: 10.1016/j.pharmthera.2024.108710. Epub ahead of print. PMID: 39179117.
29. Stadler JT, Bärnthaler T, Borenich A, Emrich IE, Habisch H, Rani A, Holzer M, Madl T, Heine GH, Marsche G. Low LCAT Activity is Linked to Acute Decompensated Heart Failure and Mortality in CKD patients. J Lipid Res. 2024 Aug 16:100624. doi: 10.1016/j.jlr.2024.100624. Epub ahead of print. PMID: 39154733.
30. Tehlivets O, Almer G, Brunner MS, Lechleitner M, Sommer G, Kolb D, Leitinger G, Diwoky C, Wolinski H, Habisch H, Opriessnig P, Bogoni F, Pernitsch D, Kavertseva M, Bourgeois B, Kukilo J, Tehlivets YG, Schwarz AN, Züllig T, Bubalo V, Schauer S, Groselj-Strele A, Hoefler G, Rechberger GN, Herrmann M, Eller K, Rosenkranz AR, Madl T, Frank S, Holzapfel GA, Kratky D, Mangge H, Hörl G. Homocysteine contributes to atherogenic transformation of the aorta in rabbits in the absence of hypercholesterolemia. Biomed Pharmacother. 2024 Aug 7;178:117244. doi: 10.1016/j.biopha.2024.117244. Epub ahead of print. PMID: 39116783.
31. Hofer SJ, Daskalaki I, Bergmann M, Friščić J, Zimmermann A, Mueller MI, Abdellatif M, Nicastro R, Masser S, Durand S, Nartey A, Waltenstorfer M, Enzenhofer S, Faimann I, Gschiel V, Bajaj T, Niemeyer C, Gkikas I, Pein L, Cerrato G, Pan H, Liang Y, Tadic J, Jerkovic A, Aprahamian F, Robbins CE, Nirmalathasan N, Habisch H, Annerer E, Dethloff F, Stumpe M, Grundler F, Wilhelmi de Toledo F, Heinz DE, Koppold DA, Rajput Khokhar A, Michalsen A, Tripolt NJ, Sourij H, Pieber TR, de Cabo R, McCormick MA, Magnes C, Kepp O, Dengjel J, Sigrist SJ, Gassen NC, Sedej S, Madl T, De Virgilio C, Stelzl U, Hoffmann MH, Eisenberg T, Tavernarakis N, Kroemer G, Madeo F. Spermidine is essential for fasting-mediated autophagy and longevity. Nat Cell Biol. 2024 Aug 8. doi: 10.1038/s41556-024-01468-x. Epub ahead of print. PMID: 39117797.
32. Gil-Redondo R, Conde R, Bruzzone C, Seco ML, Bizkarguenaga M, González-Valle B, de Diego A, Laín A, Habisch H, Haudum C, Verheyen N, Obermayer-Pietsch B, Margarita S, Pelusi S, Verde I, Oliveira N, Sousa A, Zabala-Letona A, Santos-Martin A, Loizaga-Iriarte A, Unda-Urzaiz M, Kazenwadel J, Berezhnoy G, Geisler T, Gawaz M, Cannet C, Schäfer H, Diercks T, Trautwein C, Carracedo A, Madl T, Valenti L, Spraul M, Lu SC, Embade N, Mato JM, Millet O. MetSCORE: a molecular metric to evaluate the risk of metabolic syndrome based on serum NMR metabolomics. Cardiovasc Diabetol. 2024 Jul 24;23(1):272. doi: 10.1186/s12933-024-02363-3. PMID: 39048982; PMCID: PMC11271192.
33. Lenihan-Geels G, Garcia Carrizo F, Leer M, Gohlke S, Oster M, Pöhle-Kronawitter S, Ott C, Chadt A, Reinisch IN, Galhuber M, Li C, Jonas W, Jähnert M, Klaus S, Al-Hasani H, Grune T, Schürmann A, Madl T, Prokesch A, Schupp M, Schulz TJ. Skeletal muscle p53-depletion uncovers a mechanism of fuel usage suppression that enables efficient energy conservation. J Cachexia Sarcopenia Muscle. 2024 Jul 15. doi: 10.1002/jcsm.13529. Epub ahead of print. PMID: 39010299.
34. Neuß T, Chen MC, Wirges N, Usluer S, Oellinger R, Lier S, Dudek M, Madl T, Jastroch M, Steiger K, Schmitz W, Einwächter H, Schmid RM. Metabolic Reprogramming Is an Initial Step in Pancreatic Carcinogenesis That Can Be Targeted to Inhibit Acinar-to-Ductal Metaplasia. Cancer Res. 2024 Jul 15;84(14):2297-2312. doi: 10.1158/0008-5472.CAN-23-2213. PMID: 39005053.
35. Pilic J, Gottschalk B, Bourgeois B, Habisch H, Koshenov Z, Oflaz FE, Erdogan YC, Miri SM, Yiğit EN, Aydın MŞ, Öztürk G, Eroglu E, Shoshan-Barmatz V, Madl T, Graier WF, Malli R. Hexokinase 1 forms rings that regulate mitochondrial fission during energy stress. Mol Cell. 2024 Jun 28:S1097-2765(24)00512-4. doi: 10.1016/j.molcel.2024.06.009. Epub ahead of print. PMID: 38981483.
36. Wittmann L, Eigenfeld M, Büchner K, Meiler J, Habisch H, Madl T, Kerpes R, Becker T, Berensmeier S, Schwaminger SP. Millifluidic magnetophoresis-based chip for age-specific fractionation: evaluating the impact of age on metabolomics and gene expression in yeast. Lab Chip. 2024 May 13. doi: 10.1039/d4lc00185k. Epub ahead of print. PMID: 38739033.
37. Kreuzer K, Birkl-Toeglhofer AM, Haybaeck J, Reiter A, Dalkner N, Fellendorf FT, Maget A, Platzer M, Seidl M, Mendel LM, Lenger M, Birner A, Queissner R, Mairinger M, Obermayer A, Kohlhammer-Dohr A, Stross TM, Häussl A, Hamm C, Schöggl H, Amberger-Otti D, Painold A, Lahousen-Luxenberger T, Leitner-Afschar B, Färber T, Mörkl S, Wagner-Skacel J, Meier-Allard N, Lackner S, Holasek S, Habisch H, Madl T, Reininghaus E, Bengesser SA. PROVIT-CLOCK: A Potential Influence of Probiotics and Vitamin B7 Add-On Treatment and Metabolites on Clock Gene Expression in Major Depression. Neuropsychobiology. 2024 May 22:1-17. doi: 10.1159/000538781. Epub ahead of print. PMID: 38776887.
38. Klobučar I, Habisch H, Klobučar L, Trbušić M, Pregartner G, Berghold A, Kostner GM, Scharnagl H, Madl T, Frank S, Degoricija V. Serum Levels of Adiponectin Are Strongly Associated with Lipoprotein Subclasses in Healthy Volunteers but Not in Patients with Metabolic Syndrome. Int J Mol Sci. 2024 May 6;25(9):5050. doi: 10.3390/ijms25095050. PMID: 38732266.
39. Klobučar I, Hofmann L, Habisch H, Lechleitner M, Klobučar L, Trbušić M, Pregartner G, Berghold A, Madl T, Frank S, Degoricija V. Advanced Oxidation Protein Products Are Strongly Associated with the Serum Levels and Lipid Contents of Lipoprotein Subclasses in Healthy Volunteers and Patients with Metabolic Syndrome. Antioxidants (Basel). 2024 Mar 11;13(3):339. doi: 10.3390/antiox13030339. PMID: 38539872.
40. Zhang F, Bischof H, Burgstaller S, Bourgeois BMR, Malli R, Madl T. Genetically encoded fluorescent sensor to monitor intracellular arginine methylation. J Photochem Photobiol B. 2024 Feb 15;252:112867. doi: 10.1016/j.jphotobiol.2024.112867. Epub ahead of print. PMID: 38368636.
41. Lackner S, Mahnert A, Moissl-Eichinger C, Madl T, Habisch H, Meier-Allard N, Kumpitsch C, Lahousen T, Kohlhammer-Dohr A, Mörkl S, Strobl H, Holasek S. Interindividual differences in aronia juice tolerability linked to gut microbiome and metabolome changes-secondary analysis of a randomized placebo-controlled parallel intervention trial. Microbiome. 2024 Mar 9;12(1):49. doi: 10.1186/s40168-024-01774-4. PMID: 38461313.
42. Akhmetshina A, Bianco V, Bradić I, Korbelius M, Pirchheim A, Kuentzel KB, Eichmann TO, Hinteregger H, Kolb D, Habisch H, Liesinger L, Madl T, Sattler W, Radović B, Sedej S, Birner-Gruenberger R, Vujić N, Kratky D. Loss of lysosomal acid lipase results in mitochondrial dysfunction and fiber switch in skeletal muscles of mice. Mol Metab. 2023 Dec 30;79:101869. doi: 10.1016/j.molmet.2023.101869. Epub ahead of print. PMID: 38160938.
43. Kumpitsch C, Fischmeister FPS, Lackner S, Holasek S, Madl T, Habisch H, Wolf A, Schöpf V, Moissl-Eichinger C. Reduced olfactory performance is associated with changed microbial diversity, oralization, and accumulation of dead biomaterial in the nasal olfactory area. Microbiol Spectr. 2024 Jan 9:e0154923. doi: 10.1128/spectrum.01549-23. Epub ahead of print. PMID: 38193689.
44. Usluer S, Galhuber M, Khanna Y, Bourgeois B, Spreitzer E, Michenthaler H, Prokesch A, Madl T. Disordered regions mediate the interaction of p53 and MRE11. Biochim Biophys Acta Mol Cell Res. 2024 Feb;1871(2):119654. doi: 10.1016/j.bbamcr.2023.119654. Epub 2023 Dec 19. PMID: 38123020.

2023
1. Klobučar I, Klobučar L, Lechleitner M, Trbušić M, Pregartner G, Berghold A, Habisch H, Madl T, Frank S, Degoricija V. Associations between Endothelial Lipase and Apolipoprotein B-Containing Lipoproteins Differ in Healthy Volunteers and Metabolic Syndrome Patients. Int J Mol Sci. 2023 Jun 26;24(13):10681. doi: 10.3390/ijms241310681. PMID: 37445857; PMCID: PMC10341652.
2. Abuja PM, Pabst D, Bourgeois B, Loibner M, Ulz C, Kufferath I, Fackelmann U, Stumptner C, Kraemer R, Madl T, Zatloukal K. Residual Humidity in Paraffin-Embedded Tissue Reduces Nucleic Acid Stability. Int J Mol Sci. 2023 Apr 28;24(9):8010. doi: 10.3390/ijms24098010. PMID: 37175716.
3. Neumann CJ, Mahnert A, Kumpitsch C, Kiu R, Dalby MJ, Kujawska M, Madl T, Kurath-Koller S, Urlesberger B, Resch B, Hall LJ, Moissl-Eichinger C. Clinical NEC prevention practices drive different microbiome profiles and functional responses in the preterm intestine. Nat Commun. 2023 Mar 11;14(1):1349. doi: 10.1038/s41467-023-36825-1. PMID: 36906612.
4. Klobučar I, Stadler JT, Klobučar L, Lechleitner M, Trbušić M, Pregartner G, Berghold A, Habisch H, Madl T, Marsche G, Frank S, Degoricija V. Associations between Endothelial Lipase, High-Density Lipoprotein, and Endothelial Function Differ in Healthy Volunteers and Metabolic Syndrome Patients. Int J Mol Sci. 2023 Jan 20;24(3):2073. doi: 10.3390/ijms24032073. PMID: 36768410.
5. Karner C, Anders I, Vejzovic D, Szkandera J, Scheipl S, Deutsch AJA, Weiss L, Vierlinger K, Kolb D, Kühberger S, Heitzer E, Habisch H, Zhang F, Madl T, Reininger-Gutmann B, Liegl-Atzwanger B, Rinner B. Targeting epigenetic features in clear cell sarcomas based on patient-derived cell lines. J Transl Med. 2023 Jan 29;21(1):54. doi: 10.1186/s12967-022-03843-4. PMID: 36710341.
6. Obermayer A, Tripolt NJ, Pferschy PN, Kojzar H, Aziz F, Müller A, Schauer M, Oulhaj A, Aberer F, Sourij C, Habisch H, Madl T, Pieber T, Obermayer-Pietsch B, Stadlbauer V, Sourij H. Efficacy and Safety of Intermittent Fasting in People With Insulin-Treated Type 2 Diabetes (INTERFAST-2)-A Randomized Controlled Trial. Diabetes Care. 2023 Feb 1;46(2):463-468. doi: 10.2337/dc22-1622. PMID: 36508320.
7. Zhang F, Rakhimbekova A, Lashley T, Madl T. Brain regions show different metabolic and protein arginine methylation phenotypes in frontotemporal dementias and Alzheimer's disease. Prog Neurobiol. 2023 Feb;221:102400. doi: 10.1016/j.pneurobio.2022.102400. Epub 2022 Dec 26. PMID: 36581185.

2022
8. Bresilla D, Habisch H, Pritišanac I, Zarse K, Parichatikanond W, Ristow M, Madl T, Madreiter-Sokolowski CT. The sex-specific metabolic signature of C57BL/6NRj mice during aging. Sci Rep. 2022 Dec 6;12(1):21050. doi: 10.1038/s41598-022-25396-8. PMID: 36473898.
9. Degoricija V, Klobučar I, Potočnjak I, Dokoza Terešak S, Vidović L, Pregartner G, Berghold A, Habisch H, Madl T, Frank S. Cholesterol Content of Very-Low-Density Lipoproteins Is Associated with 1-Year Mortality in Acute Heart Failure Patients. Biomolecules. 2022 Oct 21;12(10):1542. doi: 10.3390/biom12101542. PMID: 36291751; PMCID: PMC9599569.
10. Lenard AJ, Mulder FAA, Madl T. Solvent paramagnetic relaxation enhancement as a versatile method for studying structure and dynamics of biomolecular systems. Prog Nucl Magn Reson Spectrosc. 2022 Oct-Dec;132-133:113-139. doi: 10.1016/j.pnmrs.2022.09.001. Epub 2022 Sep 21. PMID: 36496256.
11. T. Reid Alderson, Hermann Habacher, Benjamin Bourgeois, Tobias Madl, The LEF-1 high-mobility group box adopts residual structure in its DNA-free form, Journal of Magnetic Resonance Open, Volumes 12–13, 2022, 100074, ISSN 2666-4410, https://doi.org/10.1016/j.jmro.2022.100074. In press
12. Zhou Q, Zhang F, Kerbl-Knapp J, Korbelius M, Kuentzel KB, Vujić N, Akhmetshina A, Hörl G, Paar M, Steyrer E, Kratky D, Madl T. Phosphatidylethanolamine N-Methyltransferase Knockout Modulates Metabolic Changes in Aging Mice. Biomolecules. 2022 Sep 9;12(9):1270. doi: 10.3390/biom12091270. PMID: 36139111.
13. Kreuzer K, Reiter A, Birkl-Töglhofer AM, Dalkner N, Mörkl S, Mairinger M, Fleischmann E, Fellendorf F, Platzer M, Lenger M, Färber T, Seidl M, Birner A, Queissner R, Mendel LS, Maget A, Kohlhammer-Dohr A, Häussl A, Wagner-Skacel J, Schöggl H, Amberger-Otti D, Painold A, Lahousen-Luxenberger T, Leitner-Afschar B, Haybaeck J, Habisch H, Madl T, Reininghaus E, Bengesser S. The PROVIT Study-Effects of Multispecies Probiotic Add-on Treatment on Metabolomics in Major Depressive Disorder-A Randomized, Placebo-Controlled Trial. Metabolites. 2022 Aug 21;12(8):770. doi: 10.3390/metabo12080770. PMID: 36005642.
14. Streese L, Habisch H, Deiseroth A, Carrard J, Infanger D, Schmidt-Trucksäss A, Madl T, Hanssen H. Lipoprotein Subclasses Independently Contribute to Subclinical Variance of Microvascular and Macrovascular Health. Molecules. 2022 Jul 25;27(15):4760. doi: 10.3390/molecules27154760. PMID: 35897932.
15. Oster M, Galhuber M, Krstic J, Steinhoff JS, Lenihan-Geels G, Wulff S, Kiefer MF, Petricek KM, Wowro SJ, Flores RE, Yang N, Li C, Meng Y, Reinisch I, Sommerfeld M, Weger S, Habisch H, Madl T, Schulz TJ, Prokesch A, Schupp M. Hepatic p53 is regulated by transcription factor FOXO1 and acutely controls glycogen homeostasis. J Biol Chem. 2022 Jul 19:102287. doi: 10.1016/j.jbc.2022.102287. Epub ahead of print. PMID: 35868560.
16. Klobučar I, Degoricija V, Potočnjak I, Trbušić M, Pregartner G, Berghold A, Fritz-Petrin E, Habisch H, Madl T, Frank S. HDL-apoA-II Is Strongly Associated with 1-Year Mortality in Acute Heart Failure Patients. Biomedicines. 2022 Jul 11;10(7):1668. doi: 10.3390/biomedicines10071668. PMID: 35884971.
17. Reinisch I, Klymiuk I, Michenthaler H, Moyschewitz E, Galhuber M, Krstic J, Domingo M, Zhang F, Karbiener M, Vujić N, Kratky D, Schreiber R, Schupp M, Lenihan-Geels G, Schulz TJ, Malli R, Madl T, Prokesch A. p53 Regulates a miRNA-Fructose Transporter Axis in Brown Adipose Tissue Under Fasting. Front Genet. 2022 Jun 6;13:913030. doi: 10.3389/fgene.2022.913030. PMID: 35734423
18. Galhuber M, Michenthaler H, Heininger C, Reinisch I, Nössing C, Krstic J, Kupper N, Moyschewitz E, Auer M, Heitzer E, Ulz P, Birner-Gruenberger R, Liesinger L, Lenihan-Geels GN, Oster M, Spreitzer E, Zenezini Chiozzi R, Schulz TJ, Schupp M, Madl T, Heck AJR, Prokesch A. Complementary omics strategies to dissect p53 signaling networks under nutrient stress. Cell Mol Life Sci. 2022 May 30;79(6):326. doi: 10.1007/s00018-022-04345-8. PMID: 35635656.
19. Spreitzer E, Alderson TR, Bourgeois B, Eggenreich L, Habacher H, Brahmersdorfer G, Pritišanac I, Sánchez-Murcia PA, Madl T. FOXO transcription factors differ in their dynamics and intra/intermolecular interactions. Curr Res Struct Biol. 2022 Apr 27;4:118-133. doi: 10.1016/j.crstbi.2022.04.001. PMID: 35573459; PMCID: PMC9097636.
20. Barth DA, Stanzer S, Spiegelberg JA, Bauernhofer T, Absenger G, Szkandera J, Gerger A, Smolle MA, Hutterer GC, Ahyai SA, Madl T, Posch F, Riedl JM, Klec C, Jost PJ, Kargl J, Stradner MH, Pichler M. Patterns of Peripheral Blood B-Cell Subtypes Are Associated With Treatment Response in Patients Treated With Immune Checkpoint Inhibitors: A Prospective Longitudinal Pan-Cancer Study. Front Immunol. 2022 Apr 1;13:840207. doi: 10.3389/fimmu.2022.840207. PMID: 35432362
21. Haudum CW, Kolesnik E, Colantonio C, Mursic I, Url-Michitsch M, Tomaschitz A, Glantschnig T, Hutz B, Lind A, Schweighofer N, Reiter C, Ablasser K, Wallner M, Tripolt NJ, Pieske-Kraigher E, Madl T, Springer A, Seidel G, Wedrich A, Zirlik A, Krahn T, Stauber R, Pieske B, Pieber TR, Verheyen N, Obermayer-Pietsch B, Schmidt A. Cohort profile: 'Biomarkers of Personalised Medicine' (BioPersMed): a single-centre prospective observational cohort study in Graz/Austria to evaluate novel biomarkers in cardiovascular and metabolic diseases. BMJ Open. 2022 Apr 7;12(4):e058890. doi: 10.1136/bmjopen-2021-058890. PMID: 35393327.
22. Horvath A, Traub J, Aliwa B, Bourgeois B, Madl T, Stadlbauer V. Oral Intake of L-Ornithine-L-Aspartate Is Associated with Distinct Microbiome and Metabolome Changes in Cirrhosis. Nutrients. 2022 Feb 10;14(4):748. doi: 10.3390/nu14040748. PMID: 35215398.
23. Lenard AJ, Zhou Q, Madreiter-Sokolowski C, Bourgeois B, Habacher H, Khanna Y, Madl T. EGCG Promotes FUS Condensate Formation in a Methylation-Dependent Manner. Cells. 2022 Feb 9;11(4):592. doi: 10.3390/cells11040592. PMID: 35203243.
24. Krstic J, Reinisch I, Schindlmaier K, Galhuber M, Riahi Z, Berger N, Kupper N, Moyschewitz E, Auer M, Michenthaler H, Nössing C, Depaoli MR, Ramadani-Muja J, Usluer S, Stryeck S, Pichler M, Rinner B, Deutsch AJA, Reinisch A, Madl T, Chiozzi RZ, Heck AJR, Huch M, Malli R, Prokesch A. Fasting improves therapeutic response in hepatocellular carcinoma through p53-dependent metabolic synergism. Sci Adv. 2022 Jan 21;8(3):eabh2635. doi: 10.1126/sciadv.abh2635. Epub 2022 Jan 21. PMID: 35061544.

2021
25. Zhang F, Richter G, Bourgeois B, Spreitzer E, Moser A, Keilbach A, Kotnik P, Madl T. A General Small-Angle X-ray Scattering-Based Screening Protocol for Studying Physical Stability of Protein Formulations. Pharmaceutics. 2021 Dec 28;14(1):69. doi: 10.3390/pharmaceutics14010069. PMID: 35056965.
26. Zhou Q, Kerbl-Knapp J, Zhang F, Korbelius M, Kuentzel KB, Vujić N, Akhmetshina A, Hörl G, Paar M, Steyrer E, Kratky D, Madl T. Metabolomic Profiles of Mouse Tissues Reveal an Interplay between Aging and Energy Metabolism. Metabolites. 2021 Dec 26;12(1):17. doi: 10.3390/metabo12010017. PMID: 35050139.
27. Habisch H, Zhang F, Zhou Q, Madl T. Exploring the Arginine Methylome by Nuclear Magnetic Resonance Spectroscopy. J Vis Exp. 2021 Dec 16;(178). doi: 10.3791/63245. PMID: 34978288.
28. Lohberger B, Glänzer D, Eck N, Kerschbaum-Gruber S, Mara E, Deycmar S, Madl T, Kashofer K, Georg P, Leithner A, Georg D. Activation of efficient DNA repair mechanisms after photon and proton irradiation of human chondrosarcoma cells. Sci Rep. 2021 Dec 16;11(1):24116. doi: 10.1038/s41598-021-03529-9. PMID: 34916568.
29. Usluer S, Spreitzer E, Bourgeois B, Madl T. p53 Transactivation Domain Mediates Binding and Phase Separation with Poly-PR/GR. Int J Mol Sci. 2021 Oct 22;22(21):11431. doi: 10.3390/ijms222111431. PMID: 34768862.
30. Lenard AJ, Hutten S, Zhou Q, Usluer S, Zhang F, Bourgeois BMR, Dormann D, Madl T. Phosphorylation Regulates CIRBP Arginine Methylation, Transportin-1 Binding and Liquid-Liquid Phase Separation. Front Mol Biosci. 2021 Oct 19;8:689687. doi: 10.3389/fmolb.2021.689687. PMID: 34738012; PMCID: PMC8562343.
31. Wahida A, Müller M, Hiergeist A, Popper B, Steiger K, Branca C, Tschurtschenthaler M, Engleitner T, Donakonda S, De Coninck J, Öllinger R, Pfautsch MK, Müller N, Silva M, Usluer S, Oberg ET, Böttcher JP, Pfarr N, Anton M, Slotta-Huspenina JB, Nerlich AG, Madl T, Basic M, Bleich A, Berx G, Ruland J, Knolle PA, Rad R, Adolph TE, Vandenabeele P, Kanegane H, Gessner A, Jost PJ, Yabal M. XIAP restrains TNF-driven intestinal inflammation and dysbiosis by promoting innate immune responses of Paneth and dendritic cells. Sci Immunol. 2021 Nov 5;6(65):eabf7235. doi: 10.1126/sciimmunol.abf7235. Epub 2021 Nov 5. PMID: 34739338.
32. Madl T. Intracellular drug binding affinities by NMR. Acta Crystallogr D Struct Biol. 2021 Oct 1;77(Pt 10):1216-1217. doi: 10.1107/S2059798321010135. Epub 2021 Oct 1. PMID: 34605425; PMCID: PMC8489227.
33. Reisinger AC, Posch F, Hackl G, Marsche G, Sourij H, Bourgeois B, Eller K, Madl T, Eller P. Branched-Chain Amino Acids Can Predict Mortality in ICU Sepsis Patients. Nutrients. 2021 Sep 3;13(9):3106. doi: 10.3390/nu13093106. PMID: 34578983.
34. Gubensäk N, Schrank E, Hartlmüller C, Göbl C, Falsone FS, Becker W, Wagner GE, Pulido S, Meyer NH, Pavkov-Keller T, Madl T, Reidl J, Zangger K. Structural and DNA binding properties of the cytoplasmic domain of Vibrio cholerae transcription factor ToxR. J Biol Chem. 2021 Sep 3:101167. doi: 10.1016/j.jbc.2021.101167. Epub ahead of print. PMID: 34487759.
35. Liu S, Hu Q, Li C, Zhang F, Gu H, Wang X, Li S, Xue L, Madl T, Zhang Y, Zhou L. Wide-Range, Rapid, and Specific Identification of Pathogenic Bacteria by Surface-Enhanced Raman Spectroscopy. ACS Sens. 2021 Aug 27;6(8):2911-2919. doi: 10.1021/acssensors.1c00641. Epub 2021 Jul 20. PMID: 34282892.
36. Streese L, Springer AM, Deiseroth A, Carrard J, Infanger D, Schmaderer C, Schmidt-Trucksäss A, Madl T, Hanssen H. Metabolic profiling links cardiovascular risk and vascular end organ damage. Atherosclerosis. 2021 Aug;331:45-53. doi: 10.1016/j.atherosclerosis.2021.07.005. Epub 2021 Jul 13. PMID: 34344526.
37. Kumpitsch C, Fischmeister FPS, Mahnert A, Lackner S, Wilding M, Sturm C, Springer A, Madl T, Holasek S, Högenauer C, Berg IA, Schoepf V, Moissl-Eichinger C. Reduced B12 uptake and increased gastrointestinal formate are associated with archaeome-mediated breath methane emission in humans. Microbiome. 2021 Sep 24;9(1):193. doi: 10.1186/s40168-021-01130-w. PMID: 34560884.
38. Zhang F, Kerbl-Knapp J, Rodriguez Colman MJ, Meinitzer A, Macher T, Vujić N, Fasching S, Jany-Luig E, Korbelius M, Kuentzel KB, Mack M, Akhmetshina A, Pirchheim A, Paar M, Rinner B, Hörl G, Steyrer E, Stelzl U, Burgering B, Eisenberg T, Pertschy B, Kratky D, Madl T, Global analysis of protein arginine methylation. Cell Reports Methods. 2021 doi: 10.1016/j.crmeth.2021.100016
39. Bourgeois B, Gui T, Hoogeboom D, Hocking H, Richter G, Spreitzer E, Viertler M, Richter K, Madl T, Burgering BMT. Multiple regulatory intrinsically disordered motifs control FOXO4 transcription factor binding and function. Cell Rep. 2021 Jul 27;36(4):109446. doi: 10.1016/j.celrep.2021.109446. PMID: 34320339.
40. Zhou Q, Usluer S, Zhang F, Lenard AJ, Bourgeois BMR, Madl T. ATP regulates RNA-driven cold inducible RNA binding protein phase separation. Protein Sci. 2021 Jul;30(7):1438-1453. doi: 10.1002/pro.4123. Epub 2021 May 22. PMID: 33991007; PMCID: PMC8197425.
41. Zhang F, Wang Y, Chen G, Li Z, Xing X, Putz-Bankuti C, Stauber RE, Liu X, Madl T. Growing Human Hepatocellular Tumors Undergo a Global Metabolic Reprogramming. Cancers (Basel). 2021 Apr 20;13(8):1980. doi: 10.3390/cancers13081980. PMID: 33924061.
42. Schroeder S, Hofer SJ, Zimmermann A, Pechlaner R, Dammbrueck C, Pendl T, Marcello GM, Pogatschnigg V, Bergmann M, Müller M, Gschiel V, Ristic S, Tadic J, Iwata K, Richter G, Farzi A, Üçal M, Schäfer U, Poglitsch M, Royer P, Mekis R, Agreiter M, Tölle RC, Sótonyi P, Willeit J, Mairhofer B, Niederkofler H, Pallhuber I, Rungger G, Tilg H, Defrancesco M, Marksteiner J, Sinner F, Magnes C, Pieber TR, Holzer P, Kroemer G, Carmona-Gutierrez D, Scorrano L, Dengjel J, Madl T, Sedej S, Sigrist SJ, Rácz B, Kiechl S, Eisenberg T, Madeo F. Dietary spermidine improves cognitive function. Cell Rep. 2021 Apr 13;35(2):108985. doi: 10.1016/j.celrep.2021.108985. PMID: 33852843.
43. Neuwirt E, Gorka O, Saller BS, Groß CJ, Madl T, Groß O. NLRP3 as a sensor of metabolism gone awry. Curr Opin Biotechnol. 2021 Apr 12;68:300-309. doi: 10.1016/j.copbio.2021.03.009. Epub ahead of print. PMID: 33862489.
44. Bischof H, Burgstaller S, Springer A, Matt L, Rauter T, Bachkönig OA, Schmidt T, Groschner K, Schindl R, Madl T, Plesnila N, Lukowski R, Graier WF, Malli R. Potassium ions promote hexokinase-II dependent glycolysis. iScience. 2021 Mar 22;24(4):102346. doi: 10.1016/j.isci.2021.102346. PMID: 33870140; PMCID: PMC8047173.
45. Joshi L, Plastira I, Bernhart E, Reicher H, Koyani CN, Madl T, Madreiter-Sokolowski C, Koshenov Z, Graier WF, Hallström S, Sattler W. Lysophosphatidic Acid Induces Aerobic Glycolysis, Lipogenesis, and Increased Amino Acid Uptake in BV-2 Microglia. Int J Mol Sci. 2021 Feb 17;22(4):1968. doi: 10.3390/ijms22041968. PMID: 33671212.
46. Zhang F, Kerbl-Knapp J, Akhmetshina A, Korbelius M, Kuentzel KB, Vujić N, Hörl G, Paar M, Kratky D, Steyrer E, Madl T. Tissue-Specific Landscape of Metabolic Dysregulation during Ageing. Biomolecules. 2021 Feb 7;11(2):235. doi: 10.3390/biom11020235. PMID: 33562384.
47. Hinteregger B, Loeffler T, Flunkert S, Neddens J, Bayer TA, Madl T, Hutter-Paier B. Metabolic, Phenotypic, and Neuropathological Characterization of the Tg4-42 Mouse Model for Alzheimer's Disease. J Alzheimers Dis. 2021 Feb 25. doi: 10.3233/JAD-201204. Epub ahead of print. PMID: 33646155.
48. Klionsky DJ, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition). Autophagy. 2021 Feb 8:1-382. doi: 10.1080/15548627.2020.1797280. Epub ahead of print. PMID: 33634751.
49. Schilcher I, Stadler JT, Lechleitner M, Hrzenjak A, Berghold A, Pregartner G, Lhomme M, Holzer M, Korbelius M, Reichmann F, Springer A, Wadsack C, Madl T, Kratky D, Kontush A, Marsche G, Frank S. Endothelial Lipase Modulates Paraoxonase 1 Content and Arylesterase Activity of HDL. Int J Mol Sci. 2021 Jan 13;22(2):E719. doi: 10.3390/ijms22020719. PMID: 33450841.
50. Schmid PWN, Lim NCH, Peters C, Back KC, Bourgeois B, Pirolt F, Richter B, Peschek J, Puk O, Amarie OV, Dalke C, Haslbeck M, Weinkauf S, Madl T, Graw J, Buchner J. Imbalances in the eye lens proteome are linked to cataract formation. Nat Struct Mol Biol. 2021 Jan 11. doi: 10.1038/s41594-020-00543-9. Epub ahead of print. PMID: 33432246.
51. Richter G, Gui T, Bourgeois B, Koyani CN, Ulz P, Heitzer E, von Lewinski D, Burgering BMT, Malle E, Madl T. β-catenin regulates FOXP2 transcriptional activity via multiple binding sites. FEBS J. 2020 Dec 7. doi: 10.1111/febs.15656. Epub ahead of print. PMID: 33284517.