Short Description
The Chirascan VX (Applied Photophysics) is a modern spectropolarimeter covering a wavelength range of 160 to 950 nm, enabling both far-UV and near-UV measurements. It is equipped with a photoelastic modulator (PEM) for high-sensitivity circular dichroism (CD) detection and records CD and absorbance simultaneously. The instrument uses an optics-based, multiwavelength calibration and does not need external standards. A Peltier-controlled cuvette holder allows precise temperature ramps (5 to 95 °C) for thermal stability measurements. The software includes an analysis program for thermal stability measurements. The instrument is integrated with a nitrogen generator (Peak Scientific Genius 1053).
https://www.photophysics.com/product-pages/chirascan-vx/
Contact Person
Univ.-Prof. Dr. Kerstin Blank
Research Services
The device is available within the framework of a scientific collaboration.
Methods & Expertise for Research Infrastructure
- Determination of the secondary and tertiary structure of proteins
- Stability measurements of proteins and nucleic acids (e.g., thermal denaturation)
- Interaction measurements of macromolecules (peptides, proteins, nucleic acids)
- Conformational analysis of small chiral molecules and chiral synthetic polymers