Short Description
The Agilent 7890 GC coupled with an Agilent 5977 single quadrupole mass spectrometer with PAL 3 autosampler enables the sensitive detection of volatile and semi-volatile compounds in the ppb range using solid-phase micro-extraction (SPME).
Unknown substances can be selectively enriched, identified using various ionisation techniques (EI and CI) and quantified over a wide concentration range using SIM and simultaneous FID detection.
Contact Person
Miriam Ressler
Research Services
Core areas are the development of analytical methods for in-process optimization during product development, the quantification of volatile and semi-volatile target compounds (e.g. active pharmaceutical ingredients) and their degradation products, suitability testing of packaging materials and polymer-based raw materials, extractables/leachables screenings in the pharmaceutical sector, residual solvent measurements and the analysis of product-specific flavors and off-flavors.
The use of different detection methods allows the evaluation of quantitative analysis results, especially for untargeted screenings and the associated multivariate data analysis.
Methods & Expertise for Research Infrastructure
The SPME method has a wide range of applications for automated sample preparation and analyte enrichment and is used for various purposes according to inhouse validated methods:
- Flavour profiles and terpene or terpenoid screening
- Temperature-dependent analysis and stress testing of medical devices, recyclates, process materials for aseptic filling, food and pharmaceutical packaging (primary and secondary packaging)
- Sensitive detection of migratable packaging ingredients (leachables) in complex sample matrices
Allocation to research infrastructure
Please contact us at: miriam.ressler@fh-joanneum.at