Oroboros Instruments

Oroboros Instruments

Innsbruck | Website

Open for Collaboration

Short Description

The Oroboros is the Bioenergetics Platform for high-resolution respirometry (HRR) for mitochondria and cell research, unique for precision OXPHOS analysis at controlled oxygen levels using small amounts of biological sample.

Research areas: fundamental bioenergetics, analysis of mitochondrial and metabolic diseases, field of preventive mitochondrial medicine.

Find solutions for and study mitochondrial function in cancer, diabetes, aging, neurodegeneration, exercise physiology and mitochondrial medicine.

Research Services

OXPHOS Analysis of mitochondrial function in disease and healthy controls.

Methods & Expertise for Research Infrastructure

The Oroboros is the Bioenergetics Platform for high-resolution respirometry (HRR) for mitochondria and cell research, unique for precision OXPHOS analysis at controlled oxygen levels using small amounts of biological sample. The Oroboros is available as two models: Oroboros NextGen-O2k and Oroboros O2k. Both provide the basis for HRR, supported by the DatLab software, with high flexibility for add-on Modules.

Both Oroboros models provide the basis for HRR applications combined with measurement of ROS production, mitochondrial membrane potential, ATP production, Ca2+, pH, and PhotoBiology. All Oroboros Modules are supported by the Oroboros NextGen-O2k, which is the only model supporting the Redox Modules (Q-Module and NADH-Module), and the NO-Module.

Small amounts of biological samples can be used for bioenergetic and OXPHOS analysis, ranging from isolated mitochondria, permeabilized tissues and permeabilized cells, to living cells and tissues slices.

The globally tested and trusted high-resolution Oroboros prioritizes both quality and scientific research output in the field of mitochondrial physiology and pathology, extended to PhotoBiology. The Oroboros is a robust sole-source instrument with a long life time and low running costs. Expert service is provided by the Oroboros Open Support.

The modular concept is supported by the specially developed Oroboros Software, DatLab, guiding the user step-by-step through the desired experiment. In addition, international Oroboros Workshops are provided on a regular basis, allowing for hands-on practical training.

Oroboros Instruments boasts over 30 years of experience and offers the leading instrument on the market in mitochondrial physiology and pathology. The Oroboros is developed and produced in Austria by Oroboros Instruments in close cooperation with WGT-Elektronik GmbH & Co KG.

The Oroboros Network includes and connects reference laboratories worldwide and labs, hospitals, research centers, pharmaceutical and biotech companies in over 50 countries worldwide.

For further information have a look at our website: https://www.oroboros.at