Kurzbeschreibung
The Sartorius Incucyte is a live-cell imaging and analysis system that allows researchers to monitor cellular behavior in real time within a standard tissue culture incubator. It automates time-lapse microscopy, enabling continuous imaging of living cells without disturbing the culture conditions. The system is compatible with various plate formats (e.g., 96-, 384-well), making it ideal for high-throughput and long-term experiments. Key capabilities include quantifying cell proliferation, apoptosis, cytotoxicity, and migration, as well as monitoring morphological changes.
The Incucyte supports both phase-contrast and fluorescent imaging within GFP and mCherry channels, for analyzing specific markers or reporters. It can track single-cell dynamics or population-level responses over time, offering detailed kinetic data. Applications span cancer research, immunology, virology, neuroscience, and drug screening. For example, it enables real-time tracking of immune cell killing, replication of reporter viruses, or neurite outgrowth. The accompanying software provides intuitive tools for image analysis, segmentation, and quantitative reporting.
Accessible for trained L3 personnel only, for use of phenotypical assessment of L3-level pathogens.
Ansprechperson
Anja de Bruin
Research Services
only after consultation Anja de Bruin
Methoden & Expertise zur Forschungsinfrastruktur
The Sartorius Incucyte is a live-cell imaging and analysis system that allows researchers to monitor cellular behavior in real time within a standard tissue culture incubator. It automates time-lapse microscopy, enabling continuous imaging of living cells without disturbing the culture conditions. The system is compatible with various plate formats (e.g., 96-, 384-well), making it ideal for high-throughput and long-term experiments. Key capabilities include quantifying cell proliferation, apoptosis, cytotoxicity, and migration, as well as monitoring morphological changes. The Incucyte supports both phase-contrast and fluorescent imaging within GFP and mCherry channels, for analyzing specific markers or reporters. It can track single-cell dynamics or population-level responses over time, offering detailed kinetic data. Applications span cancer research, immunology, virology, neuroscience, and drug screening. For example, it enables real-time tracking of immune cell killing, replication of reporter viruses, or neurite outgrowth. The accompanying software provides intuitive tools for image analysis, segmentation, and quantitative reporting. Accessible for trained L3 personnel only, for use of phenotypical assessment of L3-level pathogens.